West of Scotland Coronary Prevention Study
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The West of Scotland Coronary Prevention Study, also known as WOSCOPS, was a randomized, double-blind, placebo-controlled clinical trial, published in 1995. It compared 40mg of the lipid-lowering drug pravastatin to placebo in 6, 595 men who had a mean cholesterol of 7 mmol/L but no previous history of a heart attack. The study concluded that statin treatment for primary prevention reduced coronary heart disease (CHD) events by 31% after nearly five years of treatment.[1][2][3]
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References[edit]
- ^ Myat, Aung; Gershlick, A. H.; Gershlick, Tony (2012). Landmark Papers in Cardiovascular Medicine. Oxford University Press. p. 32. ISBN 978-0-19-959476-4.
- ^ "The West of Scotland Coronary Prevention Study: Long-Term Results". Medscape. Retrieved 7 April 2020.
- ^ Kashef, Mohammed Amin; Giugliano, Gregory (2017). "Legacy effect of statins: 20-year follow up of the West of Scotland Coronary Prevention Study (WOSCOPS)". Global Cardiology Science & Practice. 2016 (4): e201635. doi:10.21542/gcsp.2016.35. ISSN 2305-7823. PMC 5624184. PMID 28979904.
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