Shana O. Kelley
Shana O. Kelley | |
|---|---|
| Alma mater | Seton Hall University B.A. (1994) California Institute of Technology PhD (1999) |
| Spouse | Edward H. Sargent |
| Scientific career | |
| Institutions | University of Toronto The Scripps Research Institute |
| Thesis | Electron transfer through the DNA double helix: spectroscopic and electrochemical studies (1999) |
| Doctoral advisor | Jacqueline Barton |
| Other academic advisors | Paul Schimmel |
| Website | www |
Shana O. Kelley is a scientist and University Professor at the University of Toronto's Faculty of Pharmacy and Faculty of Medicine. Her research includes the development of new technologies for clinical diagnostics and drug delivery.[1] She will join the Departments of Chemistry and of Biomedical Engineering at Northwestern University, and will be affiliated with the International Institute for Nanotechnology at Northwestern.[2]
Education and training
Kelley received her B.S. from Seton Hall University in 1994. She pursued graduate studies in chemistry at the California Institute of Technology, where she worked with Jacqueline Barton. She graduated with her Ph.D. in 1999 with a dissertation entitled "Electron Transfer through the DNA Double Helix: Spectroscopic and Electrochemical Studies".[3]
From 1999 to 2000, Kelley was a NIH Postdoctoral Fellow at the Scripps Research Institute, where she worked with Paul Schimmel.[4][5]
Independent career
Kelley began her independent research career as an Assistant Professor in the Chemistry Department at Boston College in 2000. In 2006, she was promoted directly to the rank of Full Professor and in 2007, she joined the Leslie Dan Faculty of Pharmacy at the University of Toronto.[6]
Kelley founded a university spin-off company named GeneOhm Sciences with her graduate advisor Jacqueline Barton. GeneOhm Sciences was based on a discovery that Kelley made during her graduate studies, where she developed a method to detect mutations in DNA by modifying the DNA strands and measuring their differing conductivity.[7][8][9] GeneOhm Sciences used Kelley's discovery to create a diagnostic test for antibiotic-resistant MRSA bacteria.[10] GeneOhm was acquired by Becton Dickinson in early 2006.[11]
Kelley also founded the molecular diagnostics companies Xagenic Inc.[12]
Awards
- 2022 Guggenheim Fellowship[13][14]
- 2021 Fellow of the Royal Society of Canada[15]
- 2021 Order of Ontario[16]
- 2020 AFPC / Pfizer Research Career Award[17]
- 2018 Distinguished Visiting Fellow, Rowland Institute, Harvard University[18]
- 2017 ACS Inorganic Nanoscience Award[19]
- 2017 Somorjai Visiting Miller Professorship (UC Berkeley)[20]
- 2016 SLAS Innovation Award[21]
- 2016 NSERC Brockhouse Award[22]
- 2016 Fellow, American Institute for Medical and Biological Engineering[23]
- 2016 Fellow, Canadian Academy of Health Sciences[6]
- 2013 University of Toronto Distinguished Professor Award[6]
- 2011 Steacie Prize[24]
- 2011 University of Toronto Inventor of the Year[6]
- 2010 NSERC E.W.R Steacie Fellowship[25]
- 2008 Named one of Canada's Top 40 Under 40[26]
- 2005 Camille-Dreyfus Teacher-Scholar Award
- 2004 MIT Technology Review TR100 Top Innovator[27]
- 2004 Alfred P. Sloan Research Fellowship[6]
- 2004 NSF CAREER Award[6]
- 2000 Dreyfus New Faculty Award[6]
- 2000 Research Innovation Award[6]
Personal life
Kelley is married to fellow University of Toronto Professor Ted Sargent.[28][29] They met at a nanotechnology conference at UC Irvine, and have two children together.[30]
References
- ^ "Shana O. Kelley". University of Toronto.
- ^ "Internationally renowned researchers Shana Kelley and Ted Sargent join Northwestern – Weinberg College News". news.weinberg.northwestern.edu. Retrieved 2021-08-24.
- ^ O., Kelley, Shana (1999). Electron transfer through the DNA double helix: spectroscopic and electrochemical studies. thesis.library.caltech.edu (phd). doi:10.7907/HZ7H-AD50. Retrieved 2018-11-14.
- ^ Kelley, Shana O.; Steinberg, Sergey V.; Schimmel, Paul (2000). "Functional defects of pathogenic human mitochondrial tRNAs related to structural fragility". Nature Structural Biology. 7 (10): 862–865. doi:10.1038/79612. ISSN 1545-9985. PMID 11017193. S2CID 11745118.
- ^ Kelley, Shana O.; Steinberg, Sergey V.; Schimmel, Paul (2001-04-06). "Fragile T-stem in Disease-associated Human Mitochondrial tRNA Sensitizes Structure to Local and Distant Mutations *". Journal of Biological Chemistry. 276 (14): 10607–10611. doi:10.1074/jbc.M008320200. ISSN 0021-9258. PMID 11110797.
- ^ a b c d e f g h "Shana Kelley – Division of the Vice-President & Provost". Retrieved 2021-07-10.
- ^ Kelley, Shana O.; Jackson, Nicole M.; Hill, Michael G.; Barton, Jacqueline K. (1999). "Long-Range Electron Transfer through DNA Films". Angewandte Chemie International Edition. 38 (7): 941–945. doi:10.1002/(SICI)1521-3773(19990401)38:7<941::AID-ANIE941>3.0.CO;2-7. ISSN 1521-3773. PMID 29711858.
- ^ Kelley, S. (1999-12-15). "Single-base mismatch detection based on charge transduction through DNA". Nucleic Acids Research. 27 (24): 4830–4837. doi:10.1093/nar/27.24.4830. ISSN 1362-4962. PMC 148785. PMID 10572185.
- ^ "Patent No. US 6,221,586 B1" (PDF).
{{cite web}}: CS1 maint: url-status (link) - ^ "Shana Kelley on founding, developing life science startups". The Varsity. 2019-03-25. Retrieved 2021-07-10.
- ^ "BD Acquires GeneOhm Sciences for $230M in Bid to Bolster Infectious-Disease Play". GenomeWeb. Retrieved 2018-11-14.
- ^ "Shana Kelley: A quicker way to diagnose disease". Retrieved 2018-11-14.
- ^ "Shana Kelley Named Guggenheim Fellow". Robert R. McCormick School of Engineering and Applied Science. April 12, 2022. Retrieved April 12, 2022.
- ^ "Meet Our 2022 Fellows". John Simon Guggenheim Memorial Foundation. Retrieved April 12, 2022.
- ^ "PRESS RELEASE | THE RSC PRESENTS THE CLASS OF 2021 | The Royal Society of Canada". rsc-src.ca. Retrieved 2022-04-03.
- ^ "Ontario Newsroom". news.ontario.ca. Retrieved 2021-07-10.
- ^ "2020 AFPC Award Winners | afpc". www.afpc.info. Retrieved 2021-07-10.
- ^ "Rowland Institute Visiting Distinguished Scholar - Professor Shana Kelley". www2.rowland.harvard.edu. Retrieved 2021-07-10.
- ^ Wang, Linda (May 15, 2017). "Inorganic award to Shana Kelley". cen.acs.org. Retrieved 2021-07-10.
{{cite web}}: CS1 maint: url-status (link) - ^ "Somorjai Award". miller.berkeley.edu. Retrieved 2021-07-10.
- ^ "New Tools to Rapidly Diagnose Infections and Detect Antibiotic-Resistant Bacteria - Society for Laboratory Automation and Screening". 2020-09-24. Archived from the original on 2020-09-24. Retrieved 2021-07-10.
- ^ Government of Canada, Natural Sciences and Engineering Research Council of Canada (2016-06-28). "NSERC - Brockhouse - Winners". Natural Sciences and Engineering Research Council of Canada (NSERC). Retrieved 2021-07-10.
- ^ "Shana Kelley Shana O. Kelley, Ph.D. To be Inducted into Medical and Biological Engineering Elite - AIMBE". Retrieved 2021-07-10.
- ^ "Nanotechnology Now - Press Release: 2011 Steacie Prize awarded for nanotechnology-enabled disease diagnosis: Pharmacy's Shana Kelley third consecutive U of T professor to win prestigious science and engineering award". www.nanotech-now.com. Retrieved 2021-07-10.
- ^ Government of Canada, Natural Sciences and Engineering Research Council of Canada (2016-06-28). "NSERC - E.W.R. Steacie - Shana Kelley". Natural Sciences and Engineering Research Council of Canada (NSERC). Retrieved 2021-07-10.
- ^ "2008 – Canada's Top 40 Under 40".
{{cite web}}: CS1 maint: url-status (link) - ^ Review, MIT Technology. "Innovator Under 35: Shana Kelley, 34". MIT Technology Review. Retrieved 2018-11-14.
- ^ "Sargent wins Steacie Prize for outstanding young Canadian researcher". University of Toronto News. Retrieved 2021-06-02.
- ^ "Shana Kelley, Ted Sargent". The New York Times. 2006-07-30. ISSN 0362-4331. Retrieved 2021-06-02.
- ^ Nayyar, Anjum (February 13, 2012). "Campus couple balances challenges of work, home". University of Toronto News. Retrieved 2021-06-04.
{{cite web}}: CS1 maint: url-status (link)
External links
- Translational Biomedical Engineering Talk on September 9, 2020