PLEKHA8

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Pleckstrin homology domain containing A8 is a protein that in humans is encoded by the PLEKHA8 gene.

Further reading

• Godi A, Di Campli A, Konstantakopoulos A, Di Tullio G, Alessi DR, Kular GS, Daniele T, Marra P, Lucocq JM, De Matteis MA (2004). "FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P". Nat. Cell Biol. 6 (5): 393–404. doi:10.1038/ncb1119. PMID 15107860. S2CID 25874412.
• Vieira OV, Verkade P, Manninen A, Simons K (2005). "FAPP2 is involved in the transport of apical cargo in polarized MDCK cells". J. Cell Biol. 170 (4): 521–6. doi:10.1083/jcb.200503078. PMC 2171512. PMID 16103222.
• Vieira OV, Gaus K, Verkade P, Fullekrug J, Vaz WL, Simons K (2006). "FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin-Darby canine kidney (MDCK) cells". Proc. Natl. Acad. Sci. U.S.A. 103 (49): 18556–61. doi:10.1073/pnas.0608291103. PMC 1693701. PMID 17116893.
• D'Angelo G, Polishchuk E, Di Tullio G, Santoro M, Di Campli A, Godi A, West G, Bielawski J, Chuang CC, van der Spoel AC, Platt FM, Hannun YA, Polishchuk R, Mattjus P, De Matteis MA (2007). "Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide". Nature. 449 (7158): 62–7. Bibcode:2007Natur.449...62D. doi:10.1038/nature06097. PMID 17687330. S2CID 4387982.
• Tritz R, Hickey MJ, Lin AH, Hadwiger P, Sah DW, Neuwelt EA, Mueller BM, Kruse CA (2009). "FAPP2 gene downregulation increases tumor cell sensitivity to Fas-induced apoptosis". Biochem. Biophys. Res. Commun. 383 (2): 167–71. doi:10.1016/j.bbrc.2009.03.126. PMC 3998642. PMID 19341712.
• Cao X, Coskun U, Rössle M, Buschhorn SB, Grzybek M, Dafforn TR, Lenoir M, Overduin M, Simons K (2009). "Golgi protein FAPP2 tubulates membranes". Proc. Natl. Acad. Sci. U.S.A. 106 (50): 21121–5. Bibcode:2009PNAS..10621121C. doi:10.1073/pnas.0911789106. PMC 2795549. PMID 19940249.
• D'Angelo G, Rega LR, De Matteis MA (2012). "Connecting vesicular transport with lipid synthesis: FAPP2". Biochim. Biophys. Acta. 1821 (8): 1089–95. doi:10.1016/j.bbalip.2012.01.003. PMC 4331668. PMID 22266015.