Mycobacterium lentiflavum

Mycobacterium lentiflavum
	Fibrothorax caused by infection with M lentiflavum.
Scientific classification
Domain:	Bacteria
Phylum:	Actinomycetota
Class:	Actinomycetia
Order:	Mycobacteriales
Family:	Mycobacteriaceae
Genus:	Mycobacterium
Species:	M. lentiflavum
Binomial name
	Mycobacterium lentiflavum; Springer et al. 1996, ATCC 51985

Mycobacterium lentiflavum
Etymology: Lentus from Latin for slow, flavus, Latin for yellow.

Description

Colony characteristics

Physiology

Slow growth on Löwenstein-Jensen medium at temperatures between 22 °C and 37 °C within 3–4 weeks.
Generally resistant to isoniazid, rifampin, ethambutol and streptomycin.

Differential characteristics

Phylogenetic analysis, based on an evaluation of 16S rDNA sequences, places M. lentiflavum in an intermediate position between rapidly and slowly growing mycobacteria, closely related to Mycobacterium simiae and Mycobacterium genavense.

In young children with cervical lymphadenitis and in immunocompromised patients^[1]
One case of vertebral osteomyelitis reported
Biosafety level 2

First isolated from a patient with spondylodiscitis (vertebral osteomyelitis). Further isolates from clinical specimens were obtained due to the use of contaminated bronchoscopes. Also recovered from gastric juice, sputum and urine samples.

Strain 2186/92 = ATCC 51985 = CCUG 42422 = CCUG 42559 = CIP 105465 = DSM 44418 = JCM 13390.

^ Molteni C, Gazzola L, Cesari M, Lombardi A, Salerno F, Tortoli E, et al. Mycobacterium lentiflavum infection in immunocompetent patient. Emerg Infect Dis. 2005 Jan.

Springer et al. 1996. Isolation and characterization of a unique group of slowly growing mycobacteria: description of Mycobacterium lentiflavum sp. nov. J. Clin. Microbiol. 34, 1100–1107.

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