Deterenol
Jump to navigation
Jump to search
![]() | |
Clinical data | |
---|---|
Trade names | Betafrine |
Other names | Isopropylnorsynephrine, Isopropyloctopamine |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
Chemical and physical data | |
Formula | C11H17NO2 |
Molar mass | 195.262 g·mol−1 |
3D model (JSmol) | |
| |
|
Deterenol (also known as Isopropylnorsynephrine and Isopropyloctopamine; trade name Betafrine) is a synthetic stimulant drug which acts as a beta agonist. It has been found as an ingredient of dietary supplement products, but is banned in most countries due to risk of cardiac arrest.[1][2][3][4][5]
See also
- Halostachine
- Isoprenaline
- Isopropylamphetamine
- Methylhexanamine
- Octopamine
- Phenpromethamine
- Synephrine
- Pre-workout
References
- ^ Anderson WG (June 1983). "The sympathomimetic activity of N-isopropyloctopamine in vitro". The Journal of Pharmacology and Experimental Therapeutics. 225 (3): 553–8. PMID 6306210.
- ^ Mercader J, Wanecq E, Chen J, Carpéné C (September 2011). "Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium". Journal of Physiology and Biochemistry. 67 (3): 443–52. doi:10.1007/s13105-011-0078-2. PMID 21336650. S2CID 22449550.
- ^ Venhuis B, Keizers P, van Riel A, de Kaste D (June 2014). "A cocktail of synthetic stimulants found in a dietary supplement associated with serious adverse events". Drug Testing and Analysis. 6 (6): 578–81. doi:10.1002/dta.1664. PMID 24802503.
- ^ Zhao J, Wang M, Avula B, Khan IA (March 2018). "Detection and quantification of phenethylamines in sports dietary supplements by NMR approach". Journal of Pharmaceutical and Biomedical Analysis. 151: 347–355. doi:10.1016/j.jpba.2018.01.025. PMID 29413984. S2CID 46837518.
- ^ Cohen PA, Travis JC, Vanhee C, Ohana D, Venhuis BJ (March 2021). "Nine prohibited stimulants found in sports and weight loss supplements: deterenol, phenpromethamine (Vonedrine), oxilofrine, octodrine, beta-methylphenylethylamine (BMPEA), 1,3-dimethylamylamine (1,3-DMAA), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylbutylamine (1,3-DMBA) and higenamine". Clinical Toxicology: 1–7. doi:10.1080/15563650.2021.1894333. PMID 33755516.