DIS3

From Justapedia, unleashing the power of collective wisdom
Jump to navigation Jump to search

An Error has occurred retrieving Wikidata item for infobox Exosome complex exonuclease RRP44 or Dis3 is an enzyme that in humans is encoded by the DIS3 gene.[1][2] Its protein product is an RNase enzyme homologous to the yeast protein Rrp44, and can be part of the exosome complex in the nucleus of eukaryotic cells.[3][4]

References

  1. ^ Rozenblum E, Vahteristo P, Sandberg T, Bergthorsson JT, Syrjakoski K, Weaver D, Haraldsson K, Johannsdottir HK, Vehmanen P, Nigam S, Golberger N, Robbins C, Pak E, Dutra A, Gillander E, Stephan DA, Bailey-Wilson J, Juo SH, Kainu T, Arason A, Barkardottir RB, Nevanlinna H, Borg A, Kallioniemi OP (Apr 2002). "A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes". Hum Genet. 110 (2): 111–21. doi:10.1007/s00439-001-0646-6. PMID 11935316. S2CID 21371347.
  2. ^ Shiomi T, Fukushima K, Suzuki N, Nakashima N, Noguchi E, Nishimoto T (Jul 1998). "Human dis3p, which binds to either GTP- or GDP-Ran, complements Saccharomyces cerevisiae dis3". J Biochem. 123 (5): 883–90. doi:10.1093/oxfordjournals.jbchem.a022020. PMID 9562621.
  3. ^ "Entrez Gene: DIS3 DIS3 mitotic control homolog (S. cerevisiae)".
  4. ^ Tomecki, R.; Kristiansen, MS; Lykke-Andersen, S; Chlebowski, A; Larsen, KM; Szczesny, RJ; Drazkowska, K; Pastula, A; et al. (2010). "The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L". The EMBO Journal. 29 (14): 2342–57. doi:10.1038/emboj.2010.121. PMC 2910271. PMID 20531386.

Further reading