CFLAR
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An Error has occurred retrieving Wikidata item for infobox CASP8 and FADD-like apoptosis regulator is a protein that in humans is encoded by the CFLAR gene.[1][2] Also called c-FLIP (FLICE-like inhibitory protein).
References
- ^ Shu HB, Halpin DR, Goeddel DV (Jul 1997). "Casper is a FADD- and caspase-related inducer of apoptosis". Immunity. 6 (6): 751–63. doi:10.1016/S1074-7613(00)80450-1. PMID 9208847.
- ^ Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schroter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J (Jul 1997). "Inhibition of death receptor signals by cellular FLIP" (PDF). Nature. 388 (6638): 190–5. doi:10.1038/40657. PMID 9217161. S2CID 4341495.
Further reading
- Abe K, Kurakin A, Mohseni-Maybodi M, et al. (2001). "The complexity of TNF-related apoptosis-inducing ligand". Ann. N. Y. Acad. Sci. 926 (1): 52–63. doi:10.1111/j.1749-6632.2000.tb05598.x. PMID 11193041. S2CID 45991330.
- Dutton A, Young LS, Murray PG (2006). "The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer". Expert Opin. Ther. Targets. 10 (1): 27–35. doi:10.1517/14728222.10.1.27. PMID 16441226. S2CID 45292123.
External links
- Human CFLAR genome location and CFLAR gene details page in the UCSC Genome Browser.
- Overview of all the structural information available in the PDB for UniProt: O15519 (CASP8 and FADD-like apoptosis regulator) at the PDBe-KB.
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