Argininosuccinic acid
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Names | |
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IUPAC name
N-[{[(4S)-4-amino-4-carboxybutyl]amino}(imino)methyl]-L-aspartic acid
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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UNII | |
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Properties | |
C10H18N4O6 | |
Molar mass | 290.27312 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Argininosuccinic acid is a non-proteinogenic amino acid that is an important intermediate in the urea cycle. It is a basic amino acid.
Reactions
Some cells synthesize argininosuccinic acid from citrulline and aspartic acid and use it as a precursor for arginine in the urea cycle or citrulline-NO cycle. The enzyme that catalyzes the reaction is argininosuccinate synthetase.
Argininosuccinic acid is a precursor to fumarate in the citric acid cycle via argininosuccinate lyase.
Synonyms
Argininosuccinate
See also
Categories:
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- Basic amino acids
- Guanidines
- Dipeptides
- Urea cycle