Applause sign
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The applause sign is a behavioral pattern used to diagnose neurodegenerative diseases.
Description
The applause sign is gauged through performance of a three-clap test, where a patient is asked to clap three times. Failure to clap the correct amount of times is correlated with neurodegenerative disorders. Historically it has been used to specifically diagnose progressive supranuclear palsy, but it has also been reported as a sign of corticobasal degeneration, Parkinson's disease, and other neurodegenerative diseases.[1][2]
References
- ^ Moura, João; Santos, Ernestina (October–December 2021). "A Round of Applause: A Review of the Applause Sign". Sinapse. 21 (4): 223–229.
- ^ Luzzi, S.; Fabi, K.; Pesallaccia, M.; Silvestrini, M.; Provinciali, L. (2011-08-01). "Applause sign: is it really specific for Parkinsonian disorders? Evidence from cortical dementias". Journal of Neurology, Neurosurgery & Psychiatry. 82 (8): 830–833. doi:10.1136/jnnp.2010.224394. ISSN 0022-3050. PMID 21245475.
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