CX157
(Redirected from Tyrima)
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Routes of administration | Oral |
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Formula | C14H8F4O4S |
Molar mass | 348.27 g·mol−1 |
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CX157 (proposed trade name TriRima, formerly Tyrima) is a selective and reversible inhibitor of MAO-A (RIMA).[1] As of 2007 it was in phase II clinical trials for the treatment of depression.[2] In 2013, work on the drug was terminated.[1]
References
- ^ Fielding R, Mielach F, Free J, Pande A (2007). Pharmacokinetics and oral bioavailability of CX157, a reversible selective MAO-A inhibitor, in primates (PDF). 2007 AAPS Annual Meeting & Exposition. Archived from the original (PDF) on 2011-05-26. Retrieved 2009-06-14.
- ^ Clinical trial number NCT00739908} for "A Study of CX157 (TriRima) for the Treatment of Depression (CX157-200)" at ClinicalTrials.gov
Categories:
- Drugs not assigned an ATC code
- Drugs with non-standard legal status
- Articles without EBI source
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Reversible inhibitors of MAO-A
- Monoamine oxidase inhibitors
- Abandoned drugs
- Sulfur heterocycles
- Trifluoromethyl compounds
- Fluoroarenes
- Sulfones
- All stub articles
- Nervous system drug stubs