Steven V. Ley
Steven Ley | |
---|---|
Born | Steven Victor Ley 10 December 1945[1] |
Alma mater | Loughborough University of Technology (BSc, PhD)[2] |
Awards |
|
Scientific career | |
Institutions | |
Thesis | Studies in the chemistry of benzobicyclo systems (1972) |
Doctoral advisor | Harry Heaney[4] |
Influences | Derek Barton[5] |
Website | leygroup |
Steven Victor Ley FRS CBE FRSC (born 10 December 1945) is Professor of Organic Chemistry in the Department of Chemistry at the University of Cambridge, and is a Fellow of Trinity College, Cambridge. He was President of the Royal Society of Chemistry (2000–2002) and was made a CBE in January 2002, in the process. In 2011, he was included by The Times in the list of the "100 most important people in British science".[6][7][8][9]
Education
Ley was educated at Stamford and Loughborough University of Technology where he was awarded a Bachelor of Science and PhD.[2][4]
Research
Ley's main research field are the total synthesis of biomolecules. His group has published extensively on this topic, and has completed the synthesis of more than 140 natural target compounds, with notable examples including indanamycin, routiennocin, avermectin B1a, okadaic acid, spongistatin, thapsigargin, epothilone A, antascomicin B, bengazole A and rapamycin. His total synthesis of azadirachtin, completed in 2007, is widely regarded as one of the major landmarks in total synthesis. In the course of this work, he has also made substantial advances in many areas of organic chemistry, including the development of new catalysts, protecting groups and reagents. He is one of the inventors of TPAP, a widely employed oxidising reagent. He has also pioneered the use of immobilised reagents and flow techniques in multi-step organic synthesis. This work now incorporates flow chemistry for multistep organic synthesis applications.
Honours and awards
As of 2022[update], Ley's work of over 900 papers[10] has been recognised by about 45 major prizes and awards, the most recent of which are:
- 2022 Real Academia Nacional de Farmacia Foreign Member of the Spanish Royal Academy of Pharmacy[11]
- 2018 American Chemical Society Arthur C. Cope Award[12]
- 2014 IUPAC-Thales Nano Prize in Flow Chemistry[13]
- 2013 Franco Brittanique Prize awarded by Société Chimique de France[14]
- 2013 Longstaff Prize from the Royal Society of Chemistry[15]
- 2011 Royal Medal[3]
- 2010 Paracelsus Prize from the Swiss Chemical Society[16]
- 2009 Perkin Prize for Organic Chemistry, Royal Society of Chemistry[17]
- 2009 Tetrahedron Prize for Creativity in Organic Chemistry[18]
- 2009 Heinrich Wieland Prize awarded for outstanding achievements in the synthesis of key natural products, Boehringer Ingelheim[19]
- 2008 High Throughput Drug Discovery Methodologies Award from the Royal Society of Chemistry[20]
- 2008 Prous Institute-Overton and Meyer Award for New Technologies in Drug Discovery, European Federation of Medicinal Chemistry[21]
- 2008 Hans Herloff Inhoffen Medal, Helmholtz Zentrum für Infektionsforschung, Germany[22]
- 2007 SCI Innovation Award[citation needed]
- 2007 Paul Karrer Gold Medal (University of Zurich)
- 2007 The American Chemical Society Award for Creative Work in Synthetic Organic Chemistry[23]
- 2006 The Nagoya Gold Medal from the Banyu Life Science Foundation International, Japan[citation needed]
- 2006 Robert Robinson Award and Medal from the Royal Society of Chemistry[24]
- 2005 The Yamada-Koga Prize, Japan[citation needed]
- 2004 The Messel Medal Lecture, Society of Chemical Industry[citation needed]
- 2004 Innovation of the Year Award: Jointly with AstraZeneca, Avecia and Syngenta, Chemical Industries Association[citation needed]
- 2004 iChemE Award for Innovation in Applied Catalysis. The iAc Award[citation needed]
- 2004 Teamwork in Innovation Award from the Royal Society of Chemistry as part of Merck Chemicals Ltd; a team from Syngenta, Avecia, Cambridge University and Astrazeneca[25]
- 2004 Alexander-von-Humboldt Award, Germany[citation needed]
- 1990 Elected a Fellow of the Royal Society (FRS) in 1990[3]
- 1980 Corday-Morgan Medal and Prize of the Royal Institute of Chemistry[26]
References
- ^ Steven V. Ley at Library of Congress Authorities
- ^ a b "LEY, Prof. Steven Victor". Who's Who. ukwhoswho.com. Vol. 2015 (online ed.). A & C Black, an imprint of Bloomsbury Publishing plc. (Subscription or UK public library membership required.) (subscription required)
- ^ a b c "Professor Steven Ley CBE FMedSci FRS". London: Royal Society. Archived from the original on 17 November 2015.
- ^ a b Ley, Steven Victor (1972). Studies in the chemistry of benzobicyclo systems (PhD thesis). University of Loughborough. OCLC 801311581.
- ^ Ley, S. V.; Myers, R. M. (2002). "Sir Derek Harold Richard Barton. 8 September 1918 – 16 March 1998". Biographical Memoirs of Fellows of the Royal Society. 48: 1–23. doi:10.1098/rsbm.2002.0001. ISSN 0080-4606.
- ^ "Chemistry makes its mark on science top 100".
- ^ Video with Steven Ley: "Introducing the Innovative Technology Centre"
- ^ Ley, Steven V.; Thomas, Andrew W. (2003). "Modern Synthetic Methods for Copper-Mediated C(aryl)—O, C(aryl)—N, and C(aryl)—S Bond Formation". Angewandte Chemie International Edition. 42 (44): 5400–5449. doi:10.1002/anie.200300594. ISSN 1433-7851. PMID 14618572.
- ^ "Professor Steven V. Ley CBE FRS Organic Chemistry Research Group". University of Cambridge. Archived from the original on 27 September 2015.
- ^ Steven V. Ley's publications indexed by the Scopus bibliographic database. (subscription required)
- ^ "Toma de posesión como Académico Extranjero del Prof. Steven V. Ley – Real Academia Nacional de Farmacia".
- ^ "Arthur C. Cope Award: Steven V. Ley". cen.acs.org. 2018. Retrieved 2 January 2020.
- ^ "2016 IUPAC-THALESNANO PRIZE IN FLOW CHEMISTRY – CALL FOR NOMINATIONS". iupac.org. 14 September 2015. Retrieved 2 January 2020.
- ^ "List of Previous Franco-Brittanique Prize Winners". rsc.org. Retrieved 2 January 2020.
- ^ "List of Previous Longstaff Prize Winners". rsc.org. Retrieved 2 January 2020.
- ^ "List of Previous Paracelsus Winners". scg.ch. Retrieved 1 January 2020.
- ^ "List of Previous Perkin Prize Winners". rsc.org. Retrieved 2 January 2020.
- ^ "2009 Tetrahedron Prize for Creativity in Organic Chemistry, Adventures in Organic Chemistry, Steven V Ley". scg.ch. 2010. Retrieved 1 January 2020.
- ^ "Director of the Department of Chemistry, University of Cambridge, UK – Heinrich Wieland Prize 2009 for outstanding achievements in the synthesis of key natural products". heinrich-wieland-prize.de. Retrieved 7 October 2014.
- ^ "List of Previous High Throughput Drug Discovery Methodologies Award Winners". rsc.org. Retrieved 2 January 2020.
- ^ "List of Previous Prous Institute-Overton and Meyer Award Winners". efmc.info. Retrieved 2 January 2020.
- ^ "List of Previous Inhoffen Medal Winners". helmholtz-hzi.de. Retrieved 2 January 2020.
- ^ "ACS Award for Creative Work in Synthetic Organic Chemistry". cen.acs.org. Retrieved 2 January 2020.
- ^ "List of Previous Robert Robinson Winners". rsc.org. Retrieved 2 January 2020.
- ^ "List of Previous Teamwork in Innovation Award Winners". rsc.org. Retrieved 2 January 2020.
- ^ "List of Previous Corday-Morgan Medal Winners". rsc.org. Retrieved 2 January 2020.
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