Metrizoic acid
(Redirected from Metrizoate)
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Formula | C12H11I3N2O4 |
Molar mass | 627.943 g·mol−1 |
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Metrizoic acid is a pharmaceutical drug that was used as an iodinated contrast medium for X-ray imaging. Its uses included angiography[1] (imaging of blood vessels and heart chambers) and urography[2] (imaging of the urinary tract), but it has been discontinued, at least in the US.[3]
It was used in form of its salts, metrizoates. Due to its high osmolality, metrizoic acid had a risk of inducing allergic reactions higher than that of lower osmolar contrast media.[4]
References
- ^ Vik-Mo H, Danielsen R, Skinningsrud K, Haider T, Bjørkhaug A (1997). "Cardiovascular and electrocardiographic effects of iopentol in left ventricular angiography. Comparison of the low-osmolar, non-ionic iopentol (Imagopaque 350) and the hyper-osmolar, ionic metrizoate meglumine-Na-Ca (Isopaque Coronar 370) in patients with coronary heart disease". European Radiology. 7 Suppl 4: S156-61. doi:10.1007/pl00006885. PMID 9204361. S2CID 27742637.
- ^ Zachrisson BE, Jagenburg R (1983). "Comparison of iohexol with metrizoate in urography. A single blind parallel investigation". Acta Radiologica. Supplementum. 366: 30–7. PMID 6147958.
- ^ "Metrizoic acid - DrugBank". Retrieved 3 March 2017.
- ^ "Metrizoic acid - C12H11I3N2O4 - PubChem". Retrieved 3 March 2017.